TopoResponse tests whether persistent-homology features add predictive value to an E(3)-equivariant PaiNN model for molecular dipole moments and polarizability tensors. Across five topology-OOD seeds, no improvement from FiLM conditioning was detected over the baseline or matched controls; Ridge and small-MLP residual probes likewise found no beneficial correction. This result is specific to the configuration studied, not a general verdict on topological data analysis.
Arrow lengths are nonlinearly scaled for visibility; the numeric magnitudes above are exact.